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  • The Neuroscience Department in Genentech is focused on "research and drug discovery in the neurodegenerative diseases". They are attempting to find a medicine that will help in any way fight against Alzheimer's Disease, Parkinson's Disease, Glaucoma and ALS. Even though they did not synthesize a drug, they have made progress in "identifying the genes and risk factors that contribute to the pathogenesis" of these disorders. ("Genentech: Research: Neuroscience")
  • The Neural Repair Affinity Group (NRAG) at the Brain Research Institute (BRI) of UCLA includes 40 scientists who research the formation of new connections of neurons (axonal sprouting) in the brain and spinal cord after an injury has occurred. They focus on neurorehabilitation and pharmacological therapies. ("Neural Repair Affinity Group")
  • The California Institute for Regenerative Medicine (CIRM) is part of the California Stem Cell Initiative. It is responsible for funding stem cell research with $3 billion dollars throughout the state of California. ("California Institute")
  • The Christopher & Dana Reeve Foundation funds over 650 researchers that investigate neuroprotection, axon growth, remyelination, axon guidance, and stem cells. Over the years, they gave away $81 million dollars to researchers. ("Areas of Research")
  • The NHNSCR (National Human Neural Stem Cell Resource) "provides neural stem cells harvested from the post-natal, post-mortem, human brain to the research community for stem cell research". (Stem Cell Research)
  • The Cleveland Lab at UCSD is focusing "on the molecular genetics of axonal growth and motor neuron disease using molecular and genetic approaches". ("The Doctoral Program")
  • NeuralStem, Inc. is a biotherapeutics company that specifically researches neural stem cell technology and how they can differentiate them into neurons and glia.  With new neurons, they can transplant them into the human body and replace old ones.  This can lead to treatments for diseases that are thought to be incurable in the CNS, such as Parkinson's Disease or ALS. The neural stem cells can replicate through 60 generations, creating billions of cells. 

NeuralStem, Inc. Timeline:

1996- NeuralStem, Inc. is founded by Karl Johe, Richard Garr, and Merrill Solomon

June 8th, 2009- Receives patent for chemicals that makes the brain grow new cells

Sept. 22, 2009- FDA permits NeuralStem to test the stem cells on 12 patients with ALS

Jan. 21, 2010- Stem cells are injected into a spinal cord for the first time in the U.S.

("Creating Cures from Stem Cell Research")

 

 

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